Article
On the state of chromatin in mammalian sperm
2026-07-10
Abstract excerpt
<h4>SUMMARY</h4> Mammalian sperm chromatin carries epigenetic information with the potential to influence offspring phenotype, making its faithful characterization essential. It has been suggested that cauda sperm preparations are contaminated by somatic chromatin, that this contamination dominates genome-wide profiles, and that valid results require pretreatment with somatic cell lysis buffer, DNase I, and dithi...
Topics
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- Animal Genetics and Reproduction
- Chromosomal and Genetic Variations
- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genomics and Chromatin Dynamics
- Pluripotent Stem Cells Research
- Reproductive Biology and Fertility
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- bed0b1ec-7373-5eeb-b823-e97c37bec77f
- DOI
- 10.64898/2026.07.09.737589
