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Article

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

1 Jan 2015

Abstract excerpt

The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation. In addition, recent sperm chromatin genome-wide dissection studies indicate the presence of a differential distribution of the genes and repetitive sequences in the protamine-condensed and...

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Share to Epigenetics and DNA Methylation
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PMID: 25926607
DOI: 10.4103/1008-682x.153302

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