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Function of sperm chromatin structural elements in fertilization and development

11 Sept 2009

Abstract excerpt

Understanding how DNA is packaged in the mammalian sperm cell has important implications for human infertility as well as for the cell biology. Recent advances in the study of mammalian sperm chromatin structure and function have altered our perception of this highly condensed, inert chromatin. Sperm DNA is packaged very tightly to protect the DNA during the transit that occurs before fertilization. However, this...

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PMID: 19748904
DOI: 10.1093/molehr/gap080

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