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Article

A novel hypothesis for histone-to-protamine transition in Bos taurus spermatozoa

29 Nov 2016

Abstract excerpt

DNA compaction with protamines in sperm is essential for successful fertilization. However, a portion of sperm chromatin remains less tightly packed with histones, which genomic location and function remain unclear. We extracted and sequenced histone-associated DNA from sperm of nine ejaculates from three bulls. We found that the fraction of retained histones varied between samples, but the variance was similar...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 27899719
DOI: 10.1530/rep-16-0441

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