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Article

Spatial mapping of human lung tissue reveals granuloma diversity and histopathological superstructure in tuberculosis

2022-08-01

Abstract excerpt

<h4>Summary</h4> The histopathological hallmark of tuberculosis (TB) is the formation of immune cell enriched aggregates called granulomas, but the scope of granuloma heterogeneity in human TB is unknown. By spatially mapping individual immune cells across large regions of TB lung tissue, we report that in addition to necrotizing granulomas, the human TB lung contains abundant non-necrotizing leukocyte aggregates...

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Literature Corpus work
bec26a49-11d1-5109-9c2d-2e7c66900887
DOI
10.1101/2022.07.31.502240
Open publication

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Spatial mapping of human lung tissue reveals granuloma diversity and histopathological superstructure in tuberculosisDOI 10.1101/2022.07.31.502240
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