Article

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

2020-06-09

Abstract excerpt

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that is distinctly characterized by granuloma formation within infected tissues. Granulomas are dynamic and organized immune cell aggregates that limit dissemination, but can also hinder bacterial clearance. Consequently, outcome in TB is influenced by how granuloma structure and composition shift the balance between these two functio...

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Literature Corpus work: 2112c905-ab85-5b3d-9c13-a1ee9b090869
DOI: 10.1101/2020.06.08.140426

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