Article

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and putative functional roles

2023-11-01

Abstract excerpt

<title>Abstract</title> <p>B cells are important in tuberculosis (TB) immunity, but their role in the human lung is understudied. Here, we characterize B cells from lung tissue and matched blood of TB patients and found they are decreased in the blood and increased in the lungs, consistent with recruitment to infected tissue, where they are located in granuloma associated lymphoid tissue (GrALT). Flow cytometry a...

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Literature Corpus work: 02d965f9-4c52-504f-a6f5-ed71a4f4f6b0
DOI: 10.21203/rs.3.rs-3337492/v1

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