Article

Glial activity load on PET (GALP) reveals persistent ‘smoldering’ inflammation in MS despite disease modifying treatment: [F-18]PBR06 study

2023-10-06

Abstract excerpt

<h4>Introduction</h4> Cortical grey (CoGM) and white matter (WM) microglial activation (MA) is involved in the pathogenesis of multiple sclerosis (MS). [F-18]PBR06 positron emission tomography (PET) targeting 18kilodalton-translocator protein (TSPO) can detect abnormal MA in MS. <h4>Aims and Objectives</h4> The goal of this study is to determine the effect of disease modifying treatment (DMT) efficacy on modulatin...

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Literature Corpus work: be4a5953-3a1a-5ef1-94c3-b5b3f7c6c821
DOI: 10.1101/2023.10.06.23295721

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