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Article

Microglia: The Missing Link to Decipher and Therapeutically Control MS Progression?

International journal of molecular sciences - 27 Mar 2021

Geladaris Anastasia, Häusler Darius, Weber Martin S

Abstract excerpt

Therapeutically controlling chronic progression in multiple sclerosis (MS) remains a major challenge. MS progression is defined as a steady loss of parenchymal and functional integrity of the central nervous system (CNS), occurring independent of relapses or focal, magnetic resonance imaging (MRI)-detectable inflammatory lesions. While it clinically surfaces in primary or secondary progressive MS, it is assumed...

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Identifiers

PMID: 33801644
DOI: 10.3390/ijms22073461
PMCID: PMC8038003

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