Article

Molecular mechanisms associated with multiple sclerosis progression, severity and phenotype

2022-10-17

Abstract excerpt

While current treatments of multiple sclerosis (MS) effectively inhibit formation of focal lesions and relapses, most patients experience progression independent of relapse activity (PIRA). To understand PIRA, we analyzed nine prospectively acquired clinical and imaging outcomes in 176 relapsing-remitting and 215 progressive MS patients and 45 healthy volunteers, along with matched cellular and >5000 protein data...

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Literature Corpus work: f29a3806-79c5-5d7a-a583-976d65088ff7
DOI: 10.1101/2022.10.14.22281095

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