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Positron emission tomography imaging of neuroinflammation in Multiple Sclerosis with a second generation translocator protein PET radioligand

2015-01-01

Abstract excerpt

This thesis describes a new approach for molecular imaging of neuroinflammation in Multiple Sclerosis (MS). My aim was to use the 2nd generation TSPO radioligand 18F-PBR111 to explore the potential of Positron Emission Tomography (PET) targeting the 18-kDa Translocator Protein (TSPO), as an in vivo biomarker of activated microglia in MS patients. This thesis addresses three research objectives. First, I characteri...

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Literature Corpus work
21d9506c-6ae1-5c4d-91e0-ee56592379f0
DOI
10.25560/25285
Open publication

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