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Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traits

2021-01-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> DNA methylation dynamics in the brain are associated with normal development and neuropsychiatric disease and differ across functionally distinct brain regions. Previous studies of genome-wide methylation differences among human brain regions focused on limited numbers of individuals and one to two brain regions. <h4>RESULTS</h4> Using GTEx samples, we have generated a reso...

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Literature Corpus work
bdfb0bc3-bcb7-5f09-a3de-8787ae8c53e9
DOI
10.1101/2021.01.02.425010
Open publication

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Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traitsDOI 10.1101/2021.01.02.425010
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