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Article

Identification of genetic variants influencing methylation in brain with pleiotropic effects on psychiatric disorders.

Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2022

Pineda-Cirera Laura, Cabana-Domínguez Judit, Lee Phil H, Fernàndez-Castillo Noèlia, Cormand Bru

Abstract excerpt

Psychiatric disorders affect 29% of the global population at least once in the lifespan, and genetic studies have proved a shared genetic basis among them, although the underlying molecular mechanisms remain largely unknown. DNA methylation plays an important role in complex disorders and, remarkably, enrichment of common genetic variants influencing allele-specific methylation (ASM) has been reported among...

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Identifiers

PMID: 34637873
DOI: 10.1016/j.pnpbp.2021.110454
PMCID: PMC10501479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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