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Article

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.

Genome biology - 15 Jun 2012

Davies Matthew N, Volta Manuela, Pidsley Ruth, Lunnon Katie, Dixit Abhishek, Lovestone Simon, Coarfa Cristian, Harris R Alan, Milosavljevic Aleksandar, Troakes Claire, Al-Sarraj Safa, Dobson Richard, Schalkwyk Leonard C, Mill Jonathan

Abstract excerpt

BACKGROUND: Dynamic changes to the epigenome play a critical role in establishing and maintaining cellular phenotype during differentiation, but little is known about the normal methylomic differences that occur between functionally distinct areas of the brain. We characterized intra- and inter-individual methylomic variation across whole blood and multiple regions of the brain from multiple donors. RESULTS:...

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Identifiers

PMID: 22703893
DOI: 10.1186/gb-2012-13-6-r43
PMCID: PMC3446315

Genes

BDNF
BMP4
EOMES
NGFR
NUMBL
PCDH9
SLIT1
SLITRK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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