Article

Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric disease heritability

2017-03-24

Abstract excerpt

Epigenetic modifications confer stable transcriptional patterns in the brain, and both normal and abnormal brain function involve specialized brain regions, yet little is known about brain region-specific epigenetic differences. Here, we compared prefrontal cortex, anterior cingulate gyrus, hippocampus and nucleus accumbens from 6 individuals, performing whole genome bisulfite sequencing for DNA methylation. In ad...

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Literature Corpus work: 9144e24a-46f5-544e-8d77-55b639a261ff
DOI: 10.1101/120386

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