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Article

DNA methylation signatures within the human brain.

American journal of human genetics - 1 Dec 2007

Ladd-Acosta Christine, Pevsner Jonathan, Sabunciyan Sarven, Yolken Robert H, Webster Maree J, Dinkins Tiffany, Callinan Pauline A, Fan Jian-Bing, Potash James B, Feinberg Andrew P

Abstract excerpt

DNA methylation is a heritable modification of genomic DNA central to development, imprinting, transcriptional regulation, chromatin structure, and overall genomic stability. Aberrant DNA methylation of individual genes is a hallmark of cancer and has been shown to play an important role in neurological disorders such as Rett syndrome. Here, we asked whether normal DNA methylation might distinguish individual...

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Identifiers

PMID: 17999367
DOI: 10.1086/524110
PMCID: PMC2276356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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