Article

Supervised and unsupervised deep learning-based approaches for studying DNA replication spatiotemporal dynamics

2024-05-14

Abstract excerpt

In eukaryotic cells, DNA replication is organised both spatially and temporally, as evidenced by the stage-specific spatial distribution of replication foci in the nucleus. Despite the genetic association of aberrant DNA replication with numerous human diseases, the labour-intensive methods employed to study DNA replication have hindered large-scale analyses of its roles in pathological processes. In this study, w...

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Literature Corpus work: bd76e93c-b089-5cbb-b384-72925b874033
DOI: 10.1101/2024.05.09.593366

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