Article
A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress
2025-07-20
Abstract excerpt
A hallmark of heart disease is gene dysregulation and reactivation of fetal gene programs. Reactivation of these fetal programs has compensatory effects during heart failure, depending on the type and stage of the underlying cardiomyopathy. Thousands of putative cardiac gene regulatory elements have been identified that may control these programs, but their functions are largely unknown. We profile genome-wide cha...
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Identifiers and source
- Literature Corpus work
- bd4bfc92-c8d1-5f47-b4be-7972b5ec8a1a
- DOI
- 10.1101/2025.07.19.665672