Article
Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture
2018-10-29
Abstract excerpt
Epigenetic processes are known to have powerful roles in organ development across biology. It has recently been found that some of the chromatin modulatory machinery essential for proper development plays a previously unappreciated role in the pathogenesis of cardiac disease in adults. Investigations using genetic and pharmacologic gain- and loss-of-function approaches have interrogated the function of distinct ep...
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Identifiers and source
- Literature Corpus work
- af265937-138a-5239-b322-d651300f067d
- DOI
- 10.12688/f1000research.15797.1