Article

An Enzymatic Toolkit for Selective Proteolysis, Detection, and Visualization of Mucin-Domain Glycoproteins

2020-06-18

Abstract excerpt

Densely O-glycosylated mucin domains are found in a broad range of cell surface and secreted proteins, where they play key physiological roles. In addition, alterations in mucin expression and glycosylation are common in a variety of human diseases, such as cancer, cystic fibrosis, and inflammatory bowel diseases. These correlations have been challenging to uncover and establish because tools that specifically pro...

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Literature Corpus work: bd2eb780-bf89-5ea9-bfe6-19be001074d1
DOI: 10.26434/chemrxiv.12476369.v1

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