Article
Structural and biochemical analyses of β-N-acetylhexosaminidase Am0868 from Akkermansia muciniphila involved in mucin degradation.
Biochemical and biophysical research communications - 3 Sept 2020
Xu Wenjuan, Yang Wenyi, Wang Yongzhong, Wang Mingzhu, Zhang Min
Abstract excerpt
β-N-acetylhexosaminidases from the gut microbes are found to be capable of cleaving the specific glycoside linkages in the process of mucin degradation that has relevance for human health. However, features of the enzyme used in regulating the sugar-degrading capacities of Akkermansia muciniphila have not been well defined. Here we reported the crystal structure of a novel β-N-acetylhexosaminidase from...
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