Article

Substrate recognition and cleavage by mucin degrading <i>O</i> -glycopeptidases from the gut microbe <i>Bacteroides caccae</i>

2025-10-15

Abstract excerpt

<h4>ABSTRACT</h4> O -glycopeptidases are enzymes that hydrolyze the peptide bonds in glycoproteins by a mechanism that involves specific recognition of O -linked glycans on the substrate. Bacteroides caccae , an accomplished mucin degrader, is a member of the human gut microbiota with sixteen genes encoding putative O -glycopeptidases in the peptidase_M60 family. At present, the diversity of substrate selectiv...

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Literature Corpus work: 0fc6a3b6-0363-5e67-a534-4ed38e28385e
DOI: 10.1101/2025.10.14.682407

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