Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ramifications of secreted mucin MUC5AC in malignant journey: a holistic view

1 Feb 2018

Abstract excerpt

Heavily glycosylated secreted mucin MUC5AC, by the virtue of its cysteine-rich repeats, can form inter- and intramolecular disulfide linkages resulting in complex polymers, which in turn craft the framework of the polymeric mucus gel on epithelial cell surfaces. MUC5AC is a molecule with versatile functional implications including barrier functions to epithelial cells, host-pathogen interaction, immune cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29415129
DOI: 10.1093/carcin/bgy019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ramifications of secreted mucin MUC5AC in malignant journey: a holistic viewPMID 29415129Read ↗

Current status of mucins in the diagnosis and therapy of cancerSemantic proximity Read ↗

MUC16: molecular analysis and its functional implications in benign and malignant conditionsSemantic proximity Read ↗

Mucin genes and the proteins they encode: structure, diversity, and regulation.Semantic proximity Read ↗

Structure, evolution, and biology of the MUC4 mucinSemantic proximity Read ↗

MUC1 and the MUCs: A Family of Human Mucins with Impact in Cancer BiologySemantic proximity Read ↗

Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5′ ElementsSemantic proximity Read ↗

Targeting MUC15 Protein in Cancer: Molecular Mechanisms and Therapeutic PerspectivesSemantic proximity Read ↗

Structure and Function of the Cell Surface (Tethered) MucinsSemantic proximity Read ↗

Role of Intestinal Mucins in Innate Host Defense Mechanisms against PathogensSemantic proximity Read ↗

Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancySemantic proximity Read ↗

Muc1 ImmunotherapySemantic proximity Read ↗

Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.