Article

Pathological Tau transmission initiated by binding lymphocyte-activation gene 3

2023-05-17

Abstract excerpt

The spread of prion-like protein aggregates is believed to be a common driver of pathogenesis in many neurodegenerative diseases. Accumulated tangles of filamentous Tau protein are considered pathogenic lesions of Alzheimer’s disease (AD) and related Tauopathies, including progressive supranuclear palsy, and corticobasal degeneration. Tau pathologies in these illnesses exhibits a clear progressive and hierarchical...

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Literature Corpus work: bd20f917-00ca-55e5-b870-5383443e593a
DOI: 10.1101/2023.05.16.541015

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