Article

Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progression

2018-03-29

Abstract excerpt

Prion diseases, Alzheimer’s disease and Parkinson’s disease (PD) are fatal degenerative disorders that share common neuropathological and biochemical features, including the aggregation of pathological protein conformers. Lymphocyte activation gene 3 (Lag3, also known as CD223) is a member of the immunoglobulin superfamily of receptors expressed on peripheral immune cells, microglia and neurons, which serves as a...

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Literature Corpus work: 399f78c7-838e-569b-bac8-2f7e188985fb
DOI: 10.1101/291401

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