Article
Human neural crest cells display molecular and phenotypic hallmarks of stem cells.
Human molecular genetics - 1 Nov 2008
Thomas Sophie, Thomas Marie, Wincker Patrick, Babarit Candice, Xu Puting, Speer Marcy C, Munnich Arnold, Lyonnet Stanislas, Vekemans Michel, Etchevers Heather C
Abstract excerpt
The fields of both developmental and stem cell biology explore how functionally distinct cell types arise from a self-renewing founder population. Multipotent, proliferative human neural crest cells (hNCC) develop toward the end of the first month of pregnancy. It is assumed that most differentiate after migrating throughout the organism, although in animal models neural crest stem cells reportedly persist in...
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