Article

The genetic architecture of osteoarthritis: insights from UK Biobank

2017-08-11

Abstract excerpt

Osteoarthritis is a common complex disease with huge public health burden. Here we perform a genome-wide association study for osteoarthritis using data across 16.5 million variants from the UK Biobank resource. Following replication and meta-analysis in up to 30,727 cases and 297,191 controls, we report 9 new osteoarthritis loci, in all of which the most likely causal variant is non-coding. For three loci, we det...

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Literature Corpus work: e8625e0d-dbb0-5370-bf98-a9a6294a20ed
DOI: 10.1101/174755

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