Article

Inter-lamin interactions control meshwork topology in a polymer-gel model of nuclear lamina

2026-03-17

Abstract excerpt

The nuclear lamina, composed of supramolecular structures of lamin proteins, is a two-dimensional protein meshwork that preserves the structural integrity, elasticity, and morphology of the nucleus. Lamins—A/C-type and B-type—assemble into dynamic, individual but interacting networks with distinct structural properties. Lamina meshwork assembly can be disrupted by lamin mutations in diseases known as laminopathies...

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Literature Corpus work: bc9dc414-7f37-5348-8193-9a5d94837c6b
DOI: 10.64898/2026.03.14.711786

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