Article
Intermediate filaments: novel assembly models and exciting new functions for nuclear lamins.
Cellular and molecular life sciences : CMLS - 1 Aug 2003
Herrmann H, Foisner R
Abstract excerpt
Intermediate filament (IF) proteins constitute a highly diverse family of fibrous proteins in metazoans, which assemble into 10-nm-thick filaments in the cytoplasm and the nucleus. Novel recent insights into the in vitro assembly mechanism have revealed principal differences in the formation of cytoplasmic and nuclear filaments. Moreover, the past years have seen dramatic developments for the nuclear specific IF...
Topics
- Humans
- Intermediate Filament Proteins
- Intermediate Filaments
- Lamins
- Macromolecular Substances
- Microscopy, Electron
- Models, Molecular
- Molecular Structure
- Mutation
