Article

Impacted Spike Frequency Adaptation Associated with Reduction of KCNQ2/3 Promotes Seizure Activity in Temporal Lobe Epilepsy

2020-09-28

Abstract excerpt

<h4>ABSTRACT</h4> Although numerous epilepsy-related genes have been identified by unbiased genome-wide screening based on samples from both animal models and patients, the druggable targets for temporal lobe epilepsy (TLE) are still limited. Meanwhile, a large number of candidate genes that might promote or inhibit seizure activities are waiting for further validation. In this study, we first analyzed two public...

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Literature Corpus work: bc85f28b-1780-572c-9789-e23ddc36b5a3
DOI: 10.1101/2020.09.25.313254

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