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Article

Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro.

Circulation research - 12 Oct 2007

Pidkovka Nataliya A, Cherepanova Olga A, Yoshida Tadashi, Alexander Matthew R, Deaton Rebecca A, Thomas James A, Leitinger Norbert, Owens Gary K

Abstract excerpt

Atherosclerosis is a vascular disease characterized by lipid deposition and inflammation within the arterial wall. Oxidized phospholipids (oxPLs), such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) and its constituents 1-palmytoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine (PGPC) are concentrated within atherosclerotic...

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PMID: 17704209
DOI: 10.1161/CIRCRESAHA.107.152736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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