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Moremi Bio Agent: Application of A Foundation Model and End-to-End Automation in the Design and Validation of Monoclonal Antibodies Targeting <i>Plasmodium falciparum</i> Invasion Complex

2025-02-14

Abstract excerpt

Malaria remains a significant global health challenge, with Plasmodium falciparum responsible for the majority of severe cases and fatalities. Targeting the parasite’s invasion mechanisms offers a promising therapeutic strategy. In this study, we leveraged a novel agentic foundational model, Moremi Bio Agent, to design monoclonal antibodies targeting the AMA1-RON2 complex, a critical component in the parasite’s i...

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Literature Corpus work
58a6c4c8-bc18-56b3-84ba-229fb41ea83d
DOI
10.1101/2025.02.12.637967
Open publication

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Moremi Bio Agent: Application of A Foundation Model and End-to-End Automation in the Design and Validation of Monoclonal Antibodies Targeting <i>Plasmodium falciparum</i> Invasion ComplexDOI 10.1101/2025.02.12.637967
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