Article

Regulation of Mechanosensor PIEZO Channel Trafficking in <i>C. elegans</i> Germline

2026-08-20

Abstract excerpt

PIEZO proteins are essential mechanotransductive ion channels, yet mechanisms governing their subcellular localization and membrane trafficking remain elusive. Here, we leverage the C. elegans germline as an in vivo imaging platform to decipher the molecular networks directing PIEZO channel dynamics. High-resolution confocal imaging of endogenously tagged PEZO-1, the C. elegans ortholog, reveals that PEZO-1 compar...

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Literature Corpus work: a3fbdc06-b1be-595a-95e3-ab2bb7fa9c07
DOI: 10.64898/2026.08.18.745541

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