Article

Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS

2023-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Understanding the molecular mechanisms of neurodegenerative diseases and finding efficient treatments have been major priorities for research and society, yet new therapeutic approaches remain essential to face the socio-economic burden caused by these devastating diseases. Protein misfolding and aggregation are involved in several neurodegenerative disorders, such as α-synuclein (αSyn) implicat...

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Literature Corpus work: bba2c197-d7e4-5974-9fc0-3bdab572468a
DOI: 10.1101/2023.12.07.570346

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