Article

Transcription factors organize into functional groups on the linear genome and in 3D chromatin

2022-04-08

Abstract excerpt

Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial proximity (using chromatin conformation capture assays) on one hand, and based on both in vivo binding as well as TF binding motifs on the other. We ascertain signi...

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Literature Corpus work: bb8be0c9-01c6-5c4e-9cf9-ea596d0d539f
DOI: 10.1101/2022.04.06.487423

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