Article

Spatially clustered pattern of transcription factor binding reveals phase-separated transcriptional condensates at super-enhancers

2023-06-21

Abstract excerpt

<h4>ABSTRACT</h4> Many transcription factors (TFs) have been shown to bind at super-enhancers, forming transcriptional condensates to activate transcription in many cellular systems. Genomic and epigenomic determinants of phase-separated transcriptional condensates are not well understood. Here we systematically analyzed DNA sequence motifs and TF binding profiles across human cell types to identify the molecular...

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Literature Corpus work: 616203e5-60a4-59f9-a2a9-3f39e0ad9fdb
DOI: 10.1101/2023.06.18.545510

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