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Article

Reprogramming of stromal fibroblasts by chemotherapy-induced secretion of IFNβ1 drives re-growth of breast cancer cells after treatment

2020-08-06

Abstract excerpt

Chemotherapy is still the standard of care for a large number of aggressive tumours including breast cancer. In breast cancer, chemotherapeutic regimens are administered in intervaled cycles of the maximum tolerated dose, allowing cancer cells to re-grow or adapt during the resting periods between cycles. However, how stromal fibroblasts impact the fate of cancer cells after chemotherapy treatment remains poorly u...

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Literature Corpus work
bb001d7c-7da8-5ae6-8ac9-dd6073ee85fa
DOI
10.1101/2020.08.05.238436
Open publication

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Reprogramming of stromal fibroblasts by chemotherapy-induced secretion of IFNβ1 drives re-growth of breast cancer cells after treatmentDOI 10.1101/2020.08.05.238436
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