Article
Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression
2023-08-24
Abstract excerpt
Type I interferons (IFNs) play a central role not only in innate immunity against viral infection, but also in the antitumour response. Apart from indirect immune-modulatory and anti-angiogenic effects, they have direct impact on cell proliferation. Particularly for cancer arising in the context of chronic inflammation, constant exposure to IFNs may constitute a strong selective pressure during tumour evolution. E...
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Identifiers and source
- Literature Corpus work
- a0eac0a4-13dd-57a2-8a4e-9539ce914034
- DOI
- 10.21203/rs.3.rs-3276415/v1