Article
DiseaseEnhancer: a resource of human disease-associated enhancer catalog.
Nucleic acids research - 4 Jan 2018
Zhang Guanxiong, Shi Jian, Zhu Shiwei, Lan Yujia, Xu Liwen, Yuan Huating, Liao Gaoming, Liu Xiaoqin, Zhang Yunpeng, Xiao Yun, Li Xia
Abstract excerpt
Large-scale sequencing studies discovered substantial genetic variants occurring in enhancers which regulate genes via long range chromatin interactions. Importantly, such variants could affect enhancer regulation by changing transcription factor bindings or enhancer hijacking, and in turn, make an essential contribution to disease progression. To facilitate better usage of published data and exploring enhancer...
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