Article

Monitoring trace levels of ctDNA using integration of variant reads

2019-01-01

Abstract excerpt

In patients with early-stage cancer, ctDNA detection rates can be low due to the presence of few or no copies of any individual mutation in each sample. Sensitivity may be increased by collecting larger plasma volumes, but this is not feasible in practice. Although cancers typically have thousands of mutations in their genome, previous analyses measured only individual or up to 32 tumour-specific mutations in plas...

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Literature Corpus work: b9d6b8db-55a4-5464-a145-fdfb8abc1629
DOI: 10.17863/cam.40703

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