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Structural variation and fusion detection using targeted sequencing data from circulating cell free DNA

2 Feb 2019

Abstract excerpt

MOTIVATION: Cancer is a complex disease that involves rapidly evolving cells, often forming multiple distinct clones. In order to effectively understand progression of a patient-specific tumor, one needs to comprehensively sample tumor DNA at multiple time points, ideally obtained through inexpensive and minimally invasive techniques. Current sequencing technologies make the 'liquid biopsy' possible, which...

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PMID: 30759232
DOI: 10.1093/nar/gkz067

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