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Evaluation of Exome Sequencing to Estimate Tumor Burden in Plasma

18 Aug 2014

Abstract excerpt

Accurate estimation of systemic tumor load from the blood of cancer patients has enormous potential. One avenue is to measure the presence of cell-free circulating tumor DNA in plasma. Various approaches have been investigated, predominantly covering hotspot mutations or customized, patient-specific assays. Therefore, we investigated the utility of using exome sequencing to monitor circulating tumor DNA levels...

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PMID: 25133800
DOI: 10.1371/journal.pone.0104417

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