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Article

Cellular-level phenotyping of tumor-immune microenvironment (TiME) in patients in vivo reveals distinct inflammation and endothelial anergy signatures

2021-06-10

Abstract excerpt

Immunotherapies have shown unprecedented clinical benefits in several malignancies 1–3 . However, clinical responses remain variable and unpredictable, indicating the need to develop predictive platforms that can improve patient stratification 4 . Phenotyping of tumors into hot, altered, or cold 5 based on assessment of only T-cell infiltration in static tumor biopsies provides suboptimal prediction of immunoth...

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Literature Corpus work
b9d58615-c464-5a2b-bfad-185862746339
DOI
10.1101/2021.06.10.447835
Open publication

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Cellular-level phenotyping of tumor-immune microenvironment (TiME) in patients in vivo reveals distinct inflammation and endothelial anergy signaturesDOI 10.1101/2021.06.10.447835
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