Article

Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma

2023-08-25

Abstract excerpt

<h4>Background</h4> Acral melanoma (AM) has distinct characteristics as compared to cutaneous melanoma and exhibits poor response to immune checkpoint inhibitors (ICI). Tumor-intrinsic mechanisms of immune exclusion have been identified in many cancers but less studied in AM. <h4>Methods</h4> We characterized clinically annotated tumors from patients diagnosed with AM at our institution in correlation with ICI r...

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Literature Corpus work: ff5e464b-1636-5f93-8acd-fde78f7dc303
DOI: 10.1101/2023.08.24.554717

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