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Article

Downregulated transcription in chromosomal domains of midbrain dopamine neurons linked to schizophrenia.

2024-11-08

Abstract excerpt

<title>Abstract</title> <p> Ventral midbrain dopaminergic neurons are a key cell type for schizophrenia pathophysiology but information about cell type-specific genomic dysregulation in diseased brains is missing. We generated a unique midbrain functional genomics resource with 111 RNA-seq and 34 Hi-C chromosomal contact libraries for Nurr1+/NeuN + dopaminergic and their surrounding Nurr1-/NeuN- nuclei, collecte...

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Literature Corpus work
b8fa01c4-e682-5555-b157-fcb59dc4d0ec
DOI
10.21203/rs.3.rs-5354582/v1
Open publication

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Downregulated transcription in chromosomal domains of midbrain dopamine neurons linked to schizophrenia.DOI 10.21203/rs.3.rs-5354582/v1
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