Article

Integrative transcriptomics reveals sexually dimorphic microRNA control of the cholinergic/neurokine interface in schizophrenia and bipolar disorder

2019-04-07

Abstract excerpt

<h4>Summary</h4> RNA-sequencing analyses are often limited to identifying lowest p-value transcripts, which does not address polygenic phenomena. To overcome this limitation, we developed an integrative approach that combines large scale transcriptomic meta-analysis of patient brain tissues with single-cell sequencing data of CNS neurons, short RNA-sequencing of human male- and female-originated cell lines, and c...

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Literature Corpus work: 4ccabff2-8396-50a7-8568-f54843751ae6
DOI: 10.1101/600932

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