Article

The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH-oxidase activity

2020-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Neutrophils express many G protein-coupled receptors (GPCRs) including the two formyl peptide receptors (FPR1 and FPR2) and the medium chain fatty acid receptor GPR84. The FPRs are known to define a hierarchy among neutrophil GPCRs, i.e., the GPCR-mediated response can be either suppressed or amplified by signals generated by FPRs. In this study, we investigated the position of GPR84 in the FPR-...

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Literature Corpus work: b8ae6758-3c4f-5553-85b6-0825c36c75e2
DOI: 10.1101/2020.11.13.381582

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