Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages

Abstract excerpt

Macrophages have emerged as a key component of the innate immune system that emigrate to peripheral tissues during gestation and in the adult organism. Their complex pathway to maturity, their unique plasiticity and their various roles as effector and regulatory cells during an immue response have been the focus of intense research. A class of surface molecules, the G-Protein coupled receptors (GPCRs) play...

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