Article

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949

2019-03-08

Abstract excerpt

Despite the steadily increased numbers of formyl peptide receptor (FPR) ligands identified over the years, few have been characterized in studies using animal disease models and even less have entered clinical trials in human subjects. A small-molecule compound, Act-389949, was however recently tested in a phase I clinical trial and found to be safe and well tolerated in healthy human subjects. The desired anti-in...

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Literature Corpus work: 6c6b6e2f-0293-5bbb-9378-6a655baaed3f
DOI: 10.1101/571604

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