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Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profiles

2024-02-12

Abstract excerpt

Pattern Recognition Receptors are key in identifying pathogenic or damaged cell-related patterns or molecules. Among these, the closely linked formyl peptide receptors FPR1 and FPR2 are believed to hold pivotal yet differing functions in immune regulation. To address the intriguing question of how these highly related receptors with a shared agonist spectrum play differing roles in modulating inflammation, we anal...

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Literature Corpus work
78eb97fb-a8b5-5b92-90f7-7da3d3a46d30
DOI
10.1101/2024.02.08.579483
Open publication

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Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profilesDOI 10.1101/2024.02.08.579483
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